Genomic Analysis of Sleeping Beauty Transposon Integration in Human Somatic Cells

The Sleeping Beauty (SB) transposon is a non-viral integrating vector system with proven efficacy for gene transfer and functional genomics. However, integration efficiency is negatively affected by the length of the transposon. To optimize the SB transposon machinery, the inverted repeats and the t...

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Detalles Bibliográficos
Autores principales: Turchiano, Giandomenico, Latella, Maria Carmela, Gogol-Döring, Andreas, Cattoglio, Claudia, Mavilio, Fulvio, Izsvák, Zsuzsanna, Ivics, Zoltán, Recchia, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229213/
https://www.ncbi.nlm.nih.gov/pubmed/25390293
http://dx.doi.org/10.1371/journal.pone.0112712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229213/
https://www.ncbi.nlm.nih.gov/pubmed/25390293
http://dx.doi.org/10.1371/journal.pone.0112712

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