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Somatic Mutations Favorable to Patient Survival Are Predominant in Ovarian Carcinomas

Somatic mutation accumulation is a major cause of abnormal cell growth. However, some mutations in cancer cells may be deleterious to the survival and proliferation of the cancer cells, thus offering a protective effect to the patients. We investigated this hypothesis via a unique analysis of the cl...

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Detalles Bibliográficos
Autores principales: Zhang, Wensheng, Edwards, Andrea, Flemington, Erik, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229214/
https://www.ncbi.nlm.nih.gov/pubmed/25390899
http://dx.doi.org/10.1371/journal.pone.0112561