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Chronic Glucocorticoid Exposure-Induced Epididymal Adiposity Is Associated with Mitochondrial Dysfunction in White Adipose Tissue of Male C57BL/6J Mice

Prolonged and excessive glucocorticoids (GC) exposure resulted from Cushing's syndrome or GC therapy develops central obesity. Moreover, mitochondria are crucial in adipose energy homeostasis. Thus, we tested the hypothesis that mitochondrial dysfunction may contribute to chronic GC exposure-in...

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Detalles Bibliográficos
Autores principales: Yu, Jie, Yu, Bing, He, Jun, Zheng, Ping, Mao, Xiangbing, Han, Guoquan, Chen, Daiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229254/
https://www.ncbi.nlm.nih.gov/pubmed/25389775
http://dx.doi.org/10.1371/journal.pone.0112628