A Polymeric Prodrug of 5-Fluorouracil-1-Acetic Acid Using a Multi-Hydroxyl Polyethylene Glycol Derivative as the Drug Carrier

PURPOSE: Macromolecular prodrugs obtained by covalently conjugating small molecular drugs with polymeric carriers were proven to accomplish controlled and sustained release of the therapeutic agents in vitro and in vivo. Polyethylene glycol (PEG) has been extensively used due to its low toxicity, lo...

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Detalles Bibliográficos
Autores principales: Li, Man, Liang, Zhen, Sun, Xun, Gong, Tao, Zhang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229301/
https://www.ncbi.nlm.nih.gov/pubmed/25389968
http://dx.doi.org/10.1371/journal.pone.0112888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229301/
https://www.ncbi.nlm.nih.gov/pubmed/25389968
http://dx.doi.org/10.1371/journal.pone.0112888

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