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Inhibition of β-catenin/p300 interaction proximalizes mouse embryonic lung epithelium

BACKGROUND: Wnt/β-catenin signaling has been suggested to regulate proximal-distal determination of embryonic lung epithelium based upon genetically modified mouse models. The previously identified and characterized small molecule inhibitor IQ1 can pharmacologically decrease the interaction between...

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Detalles Bibliográficos
Autores principales: Sasaki, Tomoyo, Kahn, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229507/
https://www.ncbi.nlm.nih.gov/pubmed/25505699
http://dx.doi.org/10.1186/s40247-014-0008-1