Serum Peak Sulfamethoxazole Concentrations Demonstrate Difficulty in Achieving a Target Range: A Retrospective Cohort Study

OBJECTIVES: Trimethoprim (TMP)/sulfamethoxazole (SMX) has consistently demonstrated great interindividual variability. Therapeutic drug monitoring may be used to optimize dosing. Optimal peak SMX concentration has been proposed as 100 to 150 μg/mL. The objective of our work was to determine the succ...

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Detalles Bibliográficos
Autores principales: Dao, Bao D., Barreto, Jason N., Wolf, Robert C., Dierkhising, Ross A., Plevak, Matthew F., Tosh, Pritish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229511/
https://www.ncbi.nlm.nih.gov/pubmed/25408788
http://dx.doi.org/10.1016/j.curtheres.2014.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229511/
https://www.ncbi.nlm.nih.gov/pubmed/25408788
http://dx.doi.org/10.1016/j.curtheres.2014.08.003

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