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Serum Peak Sulfamethoxazole Concentrations Demonstrate Difficulty in Achieving a Target Range: A Retrospective Cohort Study

OBJECTIVES: Trimethoprim (TMP)/sulfamethoxazole (SMX) has consistently demonstrated great interindividual variability. Therapeutic drug monitoring may be used to optimize dosing. Optimal peak SMX concentration has been proposed as 100 to 150 μg/mL. The objective of our work was to determine the succ...

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Detalles Bibliográficos
Autores principales:	Dao, Bao D., Barreto, Jason N., Wolf, Robert C., Dierkhising, Ross A., Plevak, Matthew F., Tosh, Pritish K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229511/ https://www.ncbi.nlm.nih.gov/pubmed/25408788 http://dx.doi.org/10.1016/j.curtheres.2014.08.003

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