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Low Concentration of Rapamycin Inhibits Hemangioma Endothelial Cell Proliferation, Migration, and Vascular Tumor Formation in Mice

BACKGROUND: Vascular endothelial cell excessive proliferation is the main biological behavior of hemangioma. Rapamycin regulates the growth of endothelial cells by inhibiting mammalian target of rapamycin (mTOR). Thus hemangioma accompanied by excessive mTOR activation should be sensitive to rapamyc...

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Detalles Bibliográficos
Autores principales: Zheng, Ningning, Ding, Xudong, Jahan, Rabita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229512/
https://www.ncbi.nlm.nih.gov/pubmed/25408787
http://dx.doi.org/10.1016/j.curtheres.2014.09.004