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Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen
BACKGROUND: Leukemia is a systemic malignancy originated from hematopoietic cells. The extracellular environment has great impacts on the survival, proliferation and dissemination of leukemia cells. The spleen is an important organ for extramedullary hematopoiesis and a common infiltration site in l...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229605/ https://www.ncbi.nlm.nih.gov/pubmed/25366136 http://dx.doi.org/10.1186/s13045-014-0071-7 |