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Plk4 Phosphorylates Ana2 to Trigger Sas6 Recruitment and Procentriole Formation
Centrioles are 9-fold symmetrical structures at the core of centrosomes and base of cilia whose dysfunction has been linked to a wide range of inherited diseases and cancer [1]. Their duplication is regulated by a protein kinase of conserved structure, the C. elegans ZYG-1 or its Polo-like kinase 4...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229625/ https://www.ncbi.nlm.nih.gov/pubmed/25264260 http://dx.doi.org/10.1016/j.cub.2014.08.061 |