Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer

BACKGROUND: Syndecan-1 (Sdc-1) shedding induced by matrix metalloproteinase-7 (MMP-7) and additional proteases has an important role in cancer development. However, the impact of Sdc-1 shedding on chemotherapeutic resistance has not been reported. METHODS: We examined Sdc-1 shedding in colorectal ca...

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Detalles Bibliográficos
Autores principales: Wang, X, Zuo, D, Chen, Y, Li, W, Liu, R, He, Y, Ren, L, Zhou, L, Deng, T, Ying, G, Ba, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229635/
https://www.ncbi.nlm.nih.gov/pubmed/25321193
http://dx.doi.org/10.1038/bjc.2014.493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229635/
https://www.ncbi.nlm.nih.gov/pubmed/25321193
http://dx.doi.org/10.1038/bjc.2014.493

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