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Shed Syndecan-1 is involved in chemotherapy resistance via the EGFR pathway in colorectal cancer

BACKGROUND: Syndecan-1 (Sdc-1) shedding induced by matrix metalloproteinase-7 (MMP-7) and additional proteases has an important role in cancer development. However, the impact of Sdc-1 shedding on chemotherapeutic resistance has not been reported. METHODS: We examined Sdc-1 shedding in colorectal ca...

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Detalles Bibliográficos
Autores principales:	Wang, X, Zuo, D, Chen, Y, Li, W, Liu, R, He, Y, Ren, L, Zhou, L, Deng, T, Ying, G, Ba, Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229635/ https://www.ncbi.nlm.nih.gov/pubmed/25321193 http://dx.doi.org/10.1038/bjc.2014.493

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