Clinical massively parallel next-generation sequencing analysis of 409 cancer-related genes for mutations and copy number variations in solid tumours

BACKGROUND: In a clinical diagnostic laboratory, we evaluated the applicability of the Ion Proton sequencer for screening 409 cancer-related genes in solid tumours. METHODS: DNA was extracted from formalin-fixed, paraffin-embedded (FFPE) tissue biopsy specimens of 55 solid tumours (20 with matched n...

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Detalles Bibliográficos
Autores principales: Singh, R R, Patel, K P, Routbort, M J, Aldape, K, Lu, X, Manekia, J, Abraham, R, Reddy, N G, Barkoh, B A, Veliyathu, J, Medeiros, L J, Luthra, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229640/
https://www.ncbi.nlm.nih.gov/pubmed/25314059
http://dx.doi.org/10.1038/bjc.2014.518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229640/
https://www.ncbi.nlm.nih.gov/pubmed/25314059
http://dx.doi.org/10.1038/bjc.2014.518

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