Differential response of head and neck cancer cell lines to TRAIL or Smac mimetics is associated with the cellular levels and activity of caspase-8 and caspase-10

BACKGROUND: Current treatment strategies for head and neck cancer are associated with significant morbidity and up to 50% of patients relapse, highlighting the need for more specific and effective therapeutics. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and Smac mimetics (SMs)...

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Detalles Bibliográficos
Autores principales: Raulf, N, El-Attar, R, Kulms, D, Lecis, D, Delia, D, Walczak, H, Papenfuss, K, Odell, E, Tavassoli, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229641/
https://www.ncbi.nlm.nih.gov/pubmed/25314064
http://dx.doi.org/10.1038/bjc.2014.521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229641/
https://www.ncbi.nlm.nih.gov/pubmed/25314064
http://dx.doi.org/10.1038/bjc.2014.521

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