Adenosine triphosphate drives head and neck cancer pain through P2X2/3 heterotrimers

INTRODUCTION: Cancer pain creates a poor quality of life and decreases survival. The basic neurobiology of cancer pain is poorly understood. Adenosine triphosphate (ATP) and the ATP ionotropic receptor subunits, P2X2 and P2X3, mediate cancer pain in animal models; however, it is unknown whether this...

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Detalles Bibliográficos
Autores principales: Ye, Yi, Ono, Kentaro, Bernabé, Daniel G, Viet, Chi T, Pickering, Victoria, Dolan, John C, Hardt, Markus, Ford, Anthony P, Schmidt, Brian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229781/
https://www.ncbi.nlm.nih.gov/pubmed/24903857
http://dx.doi.org/10.1186/2051-5960-2-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229781/
https://www.ncbi.nlm.nih.gov/pubmed/24903857
http://dx.doi.org/10.1186/2051-5960-2-62

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