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Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistance

BACKGROUND: Insulin and insulin-like growth factors (IGFs) are key regulators of metabolism and growth. Recent evidences suggest a key role of these pathways in non-classical tissues and the metabolic pathways by which these hormones exert their effects in neoplasia is unclear. AIMS: To study insuli...

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Detalles Bibliográficos
Autores principales: Aljada, Ahmad, Saleh, Ayman M, Al Suwaidan, Salem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229859/
https://www.ncbi.nlm.nih.gov/pubmed/24885964
http://dx.doi.org/10.1186/1746-1596-9-94