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Modulation of insulin/IGFs pathways by sirtuin-7 inhibition in drug-induced chemoreistance
BACKGROUND: Insulin and insulin-like growth factors (IGFs) are key regulators of metabolism and growth. Recent evidences suggest a key role of these pathways in non-classical tissues and the metabolic pathways by which these hormones exert their effects in neoplasia is unclear. AIMS: To study insuli...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229859/ https://www.ncbi.nlm.nih.gov/pubmed/24885964 http://dx.doi.org/10.1186/1746-1596-9-94 |