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Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility

INTRODUCTION: Neutrophil extracellular traps (NETs) have recently been implicated in a number of autoimmune conditions, including rheumatoid arthritis (RA). We examined the underlying signaling pathways triggering enhanced NETosis in RA and ascertained whether the products of NETosis had diagnostic...

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Detalles Bibliográficos
Autores principales: Sur Chowdhury, Chanchal, Giaglis, Stavros, Walker, Ulrich A, Buser, Andreas, Hahn, Sinuhe, Hasler, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229860/
https://www.ncbi.nlm.nih.gov/pubmed/24928093
http://dx.doi.org/10.1186/ar4579