Quantitative group testing-based overlapping pool sequencing to identify rare variant carriers

BACKGROUND: Genome-wide association studies have revealed that rare variants are responsible for a large portion of the heritability of some complex human diseases. This highlights the increasing importance of detecting and screening for rare variants. Although the massively parallel sequencing tech...

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Detalles Bibliográficos
Autores principales: Cao, Chang-Chang, Li, Cheng, Sun, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229885/
https://www.ncbi.nlm.nih.gov/pubmed/24934981
http://dx.doi.org/10.1186/1471-2105-15-195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229885/
https://www.ncbi.nlm.nih.gov/pubmed/24934981
http://dx.doi.org/10.1186/1471-2105-15-195

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