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Gene network inference by probabilistic scoring of relationships from a factorized model of interactions
Motivation: Epistasis analysis is an essential tool of classical genetics for inferring the order of function of genes in a common pathway. Typically, it considers single and double mutant phenotypes and for a pair of genes observes whether a change in the first gene masks the effects of the mutatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229904/ https://www.ncbi.nlm.nih.gov/pubmed/24931990 http://dx.doi.org/10.1093/bioinformatics/btu287 |