A new sensitive PCR assay for one-step detection of 12 IDH1/2 mutations in glioma

INTRODUCTION: Mutations in isocitrate dehydrogenase genes IDH1 or IDH2 are frequent in glioma, and IDH mutation status is a strong diagnostic and prognostic marker. Current IDH mutation screening is performed with an immunohistochemistry (IHC) assay specific for IDH1 R132H, the most common mutation....

Descripción completa

Detalles Bibliográficos
Autores principales: Catteau, Aurélie, Girardi, Hélène, Monville, Florence, Poggionovo, Cécile, Carpentier, Sabrina, Frayssinet, Véronique, Voss, Jesse, Jenkins, Robert, Boisselier, Blandine, Mokhtari, Karima, Sanson, Marc, Peyro-Saint-Paul, Hélène, Giannini, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229941/
https://www.ncbi.nlm.nih.gov/pubmed/24889502
http://dx.doi.org/10.1186/2051-5960-2-58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229941/
https://www.ncbi.nlm.nih.gov/pubmed/24889502
http://dx.doi.org/10.1186/2051-5960-2-58

Ejemplares similares