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The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells

BACKGROUND: Tumor heterogeneity and the plasticity of cancer cells present challenges for effective clinical diagnosis and therapy. Such challenges are epitomized by neuroendocrine transdifferentiation (NED) and the emergence of neuroendocrine-like cancer cells in prostate tumors. This phenomenon fr...

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Detalles Bibliográficos
Autores principales: Pernicová, Zuzana, Slabáková, Eva, Fedr, Radek, Šimečková, Šárka, Jaroš, Josef, Suchánková, Tereza, Bouchal, Jan, Kharaishvili, Gvantsa, Král, Milan, Kozubík, Alois, Souček, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229954/
https://www.ncbi.nlm.nih.gov/pubmed/24884804
http://dx.doi.org/10.1186/1476-4598-13-113