Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2

BACKGROUND: In the adult central nervous system, axonal regeneration is abortive. Regulators of microtubule dynamics have emerged as attractive targets to promote axonal growth following injury as microtubule organization is pivotal for growth cone formation. In this study, we used conditioned neuro...

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Detalles Bibliográficos
Autores principales: Liz, Márcia A, Mar, Fernando M, Santos, Telma E, Pimentel, Helena I, Marques, Ana M, Morgado, Marlene M, Vieira, Sílvia, Sousa, Vera F, Pemble, Hayley, Wittmann, Torsten, Sutherland, Calum, Woodgett, James R, Sousa, Mónica M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229956/
https://www.ncbi.nlm.nih.gov/pubmed/24923837
http://dx.doi.org/10.1186/1741-7007-12-47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229956/
https://www.ncbi.nlm.nih.gov/pubmed/24923837
http://dx.doi.org/10.1186/1741-7007-12-47

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