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Pharmacokinetic Alteration of Baclofen by Multiple Oral Administration of Herbal Medicines in Rats

The potential pharmacokinetic (PK) interaction of conventional western drug, baclofen, and oriental medications Oyaksungisan (OY) and Achyranthes bidentata radix (AB) extract for the treatment of spasticity has been evaluated. Rats were pretreated with distilled water (DW), OY, or AB extract by oral...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hwan, Park, Gi-Young, Shin, Soyoung, Kwon, Dong Rak, Seo, Won Sik, Shin, Jeong Cheol, Choi, Jin Ho, Joo, Sang Hoon, Weon, Kwon-Yeon, Min, Byung Sun, Baek, Kyung Min, Upadhyay, Mahesh, Zhao, Bing Tian, Woo, Mi Hee, Kwon, So Hee, Shin, Beom Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229966/
https://www.ncbi.nlm.nih.gov/pubmed/25530781
http://dx.doi.org/10.1155/2014/402126