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High-dimensional analysis of the aging immune system: Verification of age-associated differences in immune signaling responses in healthy donors

BACKGROUND: Single-cell network profiling (SCNP) is a multiparametric flow cytometry-based approach that simultaneously measures evoked signaling in multiple cell subsets. Previously, using the SCNP approach, age-associated immune signaling responses were identified in a cohort of 60 healthy donors....

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Detalles Bibliográficos
Autores principales: Longo, Diane M, Louie, Brent, Ptacek, Jason, Friedland, Greg, Evensen, Erik, Putta, Santosh, Atallah, Michelle, Spellmeyer, David, Wang, Ena, Pos, Zoltan, Marincola, Francesco M, Schaeffer, Andrea, Lukac, Suzanne, Railkar, Radha, Beals, Chan R, Cesano, Alessandra, Carayannopoulos, Leonidas N, Hawtin, Rachael E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229969/
https://www.ncbi.nlm.nih.gov/pubmed/24952610
http://dx.doi.org/10.1186/1479-5876-12-178