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From sequence to enzyme mechanism using multi-label machine learning

BACKGROUND: In this work we predict enzyme function at the level of chemical mechanism, providing a finer granularity of annotation than traditional Enzyme Commission (EC) classes. Hence we can predict not only whether a putative enzyme in a newly sequenced organism has the potential to perform a ce...

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Detalles Bibliográficos
Autores principales: De Ferrari, Luna, Mitchell, John BO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229970/
https://www.ncbi.nlm.nih.gov/pubmed/24885296
http://dx.doi.org/10.1186/1471-2105-15-150