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From sequence to enzyme mechanism using multi-label machine learning
BACKGROUND: In this work we predict enzyme function at the level of chemical mechanism, providing a finer granularity of annotation than traditional Enzyme Commission (EC) classes. Hence we can predict not only whether a putative enzyme in a newly sequenced organism has the potential to perform a ce...
Autores principales: | De Ferrari, Luna, Mitchell, John BO |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229970/ https://www.ncbi.nlm.nih.gov/pubmed/24885296 http://dx.doi.org/10.1186/1471-2105-15-150 |
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