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Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway

The aim of this study was to investigate whether alpha lipoic acid (LA) regulates high glucose-induced mesangial cell proliferation and extracellular matrix production via mTOR/p70S6K/4E-BP1 signaling. The effect of LA on high glucose-induced cell proliferation, fibronectin (FN), and collagen type I...

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Detalles Bibliográficos
Autores principales: Lv, Chuan, Wu, Can, Zhou, Yue-hong, Shao, Ying, Wang, Guan, Wang, Qiu-yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229972/
https://www.ncbi.nlm.nih.gov/pubmed/25530759
http://dx.doi.org/10.1155/2014/658589