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Estimation of protein function using template-based alignment of enzyme active sites

BACKGROUND: The accumulation of protein structural data occurs more rapidly than it can be characterized by traditional laboratory means. This has motivated widespread efforts to predict enzyme function computationally. The most useful/accurate strategies employed to date are based on the detection...

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Detalles Bibliográficos
Autores principales: Hanson, Brett, Westin, Charles, Rosa, Mario, Grier, Alexander, Osipovitch, Mikhail, MacDonald, Madolyn L, Dodge, Greg, Boli, Paule M, Corwin, Cyprian W, Kessler, Haeja, McKay, Talia, Bernstein, Herbert J, Craig, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229977/
https://www.ncbi.nlm.nih.gov/pubmed/24669788
http://dx.doi.org/10.1186/1471-2105-15-87