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Improving clinical trial efficiency by biomarker-guided patient selection

BACKGROUND: In many therapeutic areas, individual patient markers have been identified that are associated with differential treatment response. These markers include both baseline characteristics, as well as short-term changes following treatment. Using such predictive markers to select subjects fo...

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Detalles Bibliográficos
Autores principales: Boessen, Ruud, Heerspink, Hiddo J Lambers, De Zeeuw, Dick, Grobbee, Diederick E, Groenwold, Rolf HH, Roes, Kit CB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229992/
https://www.ncbi.nlm.nih.gov/pubmed/24690215
http://dx.doi.org/10.1186/1745-6215-15-103