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Using beta-binomial regression for high-precision differential methylation analysis in multifactor whole-genome bisulfite sequencing experiments

BACKGROUND: Whole-genome bisulfite sequencing currently provides the highest-precision view of the epigenome, with quantitative information about populations of cells down to single nucleotide resolution. Several studies have demonstrated the value of this precision: meaningful features that correla...

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Detalles Bibliográficos
Autores principales: Dolzhenko, Egor, Smith, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230021/
https://www.ncbi.nlm.nih.gov/pubmed/24962134
http://dx.doi.org/10.1186/1471-2105-15-215