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Using beta-binomial regression for high-precision differential methylation analysis in multifactor whole-genome bisulfite sequencing experiments
BACKGROUND: Whole-genome bisulfite sequencing currently provides the highest-precision view of the epigenome, with quantitative information about populations of cells down to single nucleotide resolution. Several studies have demonstrated the value of this precision: meaningful features that correla...
Autores principales: | Dolzhenko, Egor, Smith, Andrew D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230021/ https://www.ncbi.nlm.nih.gov/pubmed/24962134 http://dx.doi.org/10.1186/1471-2105-15-215 |
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