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A model-based information sharing protocol for profile Hidden Markov Models used for HIV-1 recombination detection

BACKGROUND: In many applications, a family of nucleotide or protein sequences classified into several subfamilies has to be modeled. Profile Hidden Markov Models (pHMMs) are widely used for this task, modeling each subfamily separately by one pHMM. However, a major drawback of this approach is the d...

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Detalles Bibliográficos
Autores principales: Bulla, Ingo, Schultz, Anne-Kathrin, Chesneau, Christophe, Mark, Tanya, Serea, Florin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230192/
https://www.ncbi.nlm.nih.gov/pubmed/24946781
http://dx.doi.org/10.1186/1471-2105-15-205