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Syntheses of Isoxazoline-Carbocyclic Nucleosides and Their Antiviral Evaluation: A Standard Protocol

The current synthesis of racemic purine and pyrimidine isoxazoline-carbocyclic nucleosides is reported, detailing the key-steps for standard and reliable preparations. Improved yields were obtained by the proper tuning of the single synthetic steps, opening the way for the preparation of a variety o...

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Detalles Bibliográficos
Autores principales: Quadrelli, Paolo, Vazquez Martinez, Naiara, Scrocchi, Roberto, Corsaro, Antonino, Pistarà, Venerando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230217/
https://www.ncbi.nlm.nih.gov/pubmed/25544956
http://dx.doi.org/10.1155/2014/492178