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Chronic granulomatous disease: why an inflammatory disease?

Chronic granulomatous disease is a primary immunodeficiency caused by mutations in the genes encoding subunits of the phagocytic NADPH oxidase system. Patients can present with severe, recurrent infections and noninfectious conditions. Among the latter, inflammatory manifestations are predominant, e...

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Detalles Bibliográficos
Autores principales: Roxo-Junior, P., Simão, H.M.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230281/
https://www.ncbi.nlm.nih.gov/pubmed/25296353
http://dx.doi.org/10.1590/1414-431X20143735