Determination of CYP2D6 *3, *4, and *10 frequency in women with breast cancer in São Luís, Brazil, and its association with prognostic factors and disease-free survival

The CYP2D6 enzyme is crucial for the metabolism of tamoxifen. The CYP2D6 gene is highly polymorphic, and individuals can be extensive, intermediate, or poor tamoxifen metabolizers. The aim of this study was to determine the frequencies of the CYP2D6 *3, *4, and *10 alleles in women with breast cance...

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Detalles Bibliográficos
Autores principales: Martins, D.M.F., Vidal, F.C.B., Souza, R.D.M., Brusaca, S.A., Brito, L.M.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2014
Materias:
Clinical Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230293/
https://www.ncbi.nlm.nih.gov/pubmed/25296365
http://dx.doi.org/10.1590/1414-431X20143761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230293/
https://www.ncbi.nlm.nih.gov/pubmed/25296365
http://dx.doi.org/10.1590/1414-431X20143761

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