The Simcyp Population Based Simulator: Architecture, Implementation, and Quality Assurance

Developing a user-friendly platform that can handle a vast number of complex physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) models both for conventional small molecules and larger biologic drugs is a substantial challenge. Over the last decade the Simcyp Population Based Simulat...

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Detalles Bibliográficos
Autores principales: Jamei, Masoud, Marciniak, Steve, Edwards, Duncan, Wragg, Kris, Feng, Kairui, Barnett, Adrian, Rostami-Hodjegan, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230310/
https://www.ncbi.nlm.nih.gov/pubmed/25505654
http://dx.doi.org/10.1186/2193-9616-1-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230310/
https://www.ncbi.nlm.nih.gov/pubmed/25505654
http://dx.doi.org/10.1186/2193-9616-1-9

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