Hybrid phenylthiazole and 1,3,5-triazine target cytosolic leucyl-tRNA synthetase for antifungal action as revealed by molecular docking studies

BACKGROUND: Leucyl-tRNA synthetase (LeuRS) is one of the essential enzymes belonging to the family of aminoacyl-tRNA synthetases (aaRSs), which executes the translation of genetic code by catalyzing the specific attachment of amino acids to their cognate tRNAs. This process is very crucial for survi...

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Detalles Bibliográficos
Autores principales: Singh, Udaya Pratap, Bhat, Hans Raj, Gahtori, Prashant, Singh, Ramendra K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230311/
https://www.ncbi.nlm.nih.gov/pubmed/25505648
http://dx.doi.org/10.1186/2193-9616-1-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230311/
https://www.ncbi.nlm.nih.gov/pubmed/25505648
http://dx.doi.org/10.1186/2193-9616-1-3

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