Histone deacetylase 8 is deregulated in urothelial cancer but not a target for efficient treatment

BACKGROUND: Previous studies have shown that class-I histone deacetylase (HDAC) 8 mRNA is upregulated in urothelial cancer tissues and urothelial cancer cell lines compared to benign controls. Using urothelial cancer cell lines we evaluated whether specific targeting of HDAC8 might be a therapeutic...

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Detalles Bibliográficos
Autores principales: Lehmann, Maria, Hoffmann, Michèle J, Koch, Annemarie, Ulrich, Scott M, Schulz, Wolfgang A, Niegisch, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230422/
https://www.ncbi.nlm.nih.gov/pubmed/25011684
http://dx.doi.org/10.1186/s13046-014-0059-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230422/
https://www.ncbi.nlm.nih.gov/pubmed/25011684
http://dx.doi.org/10.1186/s13046-014-0059-8

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