Modeling bioavailability to organs protected by biological barriers

Computational pharmacokinetic (PK) modeling gives access to drug concentration vs. time profiles in target organs and allows better interpretation of clinical observations of therapeutic or toxic effects. Physiologically-based PK (PBPK) models in particular, based on mechanistic descriptions of the...

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Detalles Bibliográficos
Autor principal: Quignot, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230447/
https://www.ncbi.nlm.nih.gov/pubmed/25505653
http://dx.doi.org/10.1186/2193-9616-1-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230447/
https://www.ncbi.nlm.nih.gov/pubmed/25505653
http://dx.doi.org/10.1186/2193-9616-1-8

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