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Generation of knockout rabbits using transcription activator-like effector nucleases

Zinc-finger nucleases and transcription activator-like effector nucleases are novel gene-editing platforms contributing to redefine the boundaries of modern biological research. They are composed of a non-specific cleavage domain and a tailor made DNA-binding module, which enables a broad range of g...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Fan, Nana, Song, Jun, Zhong, Juan, Guo, Xiaogang, Tian, Weihua, Zhang, Quanjun, Cui, Fenggong, Li, Li, Newsome, Philip N, Frampton, Jon, Esteban, Miguel A, Lai, Liangxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230510/
https://www.ncbi.nlm.nih.gov/pubmed/25408882
http://dx.doi.org/10.1186/2045-9769-3-3