A novel pathway of rapid TLR-triggered activation of integrin-dependent leukocyte adhesion that requires Rap1 GTPase

Rapid β2-integrin activation is indispensable for leukocyte adhesion and recruitment to sites of infection and is mediated by chemokine- or P-selectin glycoprotein ligand-1–induced inside-out signaling. Here we uncovered a novel pathway for rapid activation of integrin-dependent leukocyte adhesion,...

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Detalles Bibliográficos
Autores principales: Chung, Kyoung-Jin, Mitroulis, Ioannis, Wiessner, Johannes R., Zheng, Ying Yi, Siegert, Gabriele, Sperandio, Markus, Chavakis, Triantafyllos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230584/
https://www.ncbi.nlm.nih.gov/pubmed/25057020
http://dx.doi.org/10.1091/mbc.E14-04-0867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230584/
https://www.ncbi.nlm.nih.gov/pubmed/25057020
http://dx.doi.org/10.1091/mbc.E14-04-0867

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