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The Golgi ribbon structure facilitates anterograde transport of large cargoes

In mammalian cells, individual Golgi stacks fuse laterally to form the characteristic perinuclear ribbon structure. Yet the purpose of this remarkable structure has been an enigma. We report that breaking down the ribbon of mammalian cells strongly inhibits intra-Golgi transport of large cargoes wit...

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Detalles Bibliográficos
Autores principales: Lavieu, Gregory, Dunlop, Myun Hwa, Lerich, Alexander, Zheng, Hong, Bottanelli, Francesca, Rothman, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230591/
https://www.ncbi.nlm.nih.gov/pubmed/25103235
http://dx.doi.org/10.1091/mbc.E14-04-0931