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Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair

Dysferlin and calpain are important mediators of the emergency response to repair plasma membrane injury. Our previous research revealed that membrane injury induces cleavage of dysferlin to release a synaptotagmin-like C-terminal module we termed mini-dysferlin(C72). Here we show that injury-activa...

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Detalles Bibliográficos
Autores principales: Redpath, G. M. I., Woolger, N., Piper, A. K., Lemckert, F. A., Lek, A., Greer, P. A., North, K. N., Cooper, S. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230592/
https://www.ncbi.nlm.nih.gov/pubmed/25143396
http://dx.doi.org/10.1091/mbc.E14-04-0947