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The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells
Human Period 2 (hPer2) is a transcriptional regulator at the core of the circadian clock mechanism that is responsible for generating the negative feedback loop that sustains the clock. Its relevance to human disease is underlined by alterations in its function that affect numerous biochemical and p...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230596/ https://www.ncbi.nlm.nih.gov/pubmed/25103245 http://dx.doi.org/10.1091/mbc.E14-05-0993 |