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Modularity and predictability in cell signaling and decision making

Cells make decisions to differentiate, divide, or apoptose based on multiple signals of internal and external origin. These decisions are discrete outputs from dynamic networks comprised of signaling pathways. Yet the validity of this decomposition of regulatory proteins into distinct pathways is un...

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Detalles Bibliográficos
Autores principales: Atay, Oguzhan, Skotheim, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230600/
https://www.ncbi.nlm.nih.gov/pubmed/25368418
http://dx.doi.org/10.1091/mbc.E14-02-0718