Cargando…

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

The microtubule-associated phosphoprotein tau regulates microtubule dynamics and is involved in neurodegenerative diseases collectively called tauopathies. It is generally believed that the vast majority of tau molecules decorate axonal microtubules, thereby stabilizing them. However, it is an open...

Descripción completa

Detalles Bibliográficos
Autores principales: Janning, Dennis, Igaev, Maxim, Sündermann, Frederik, Brühmann, Jörg, Beutel, Oliver, Heinisch, Jürgen J., Bakota, Lidia, Piehler, Jacob, Junge, Wolfgang, Brandt, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230615/
https://www.ncbi.nlm.nih.gov/pubmed/25165145
http://dx.doi.org/10.1091/mbc.E14-06-1099