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Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons
The microtubule-associated phosphoprotein tau regulates microtubule dynamics and is involved in neurodegenerative diseases collectively called tauopathies. It is generally believed that the vast majority of tau molecules decorate axonal microtubules, thereby stabilizing them. However, it is an open...
Autores principales: | Janning, Dennis, Igaev, Maxim, Sündermann, Frederik, Brühmann, Jörg, Beutel, Oliver, Heinisch, Jürgen J., Bakota, Lidia, Piehler, Jacob, Junge, Wolfgang, Brandt, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230615/ https://www.ncbi.nlm.nih.gov/pubmed/25165145 http://dx.doi.org/10.1091/mbc.E14-06-1099 |
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