Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum–plasma membrane junctions

Following endoplasmic reticulum (ER) Ca(2+) depletion, STIM1 and Orai1 complexes assemble autonomously at ER–plasma membrane (PM) junctions to trigger store-operated Ca(2+) influx. One hypothesis to explain this process is a diffusion trap in which activated STIM1 diffusing in the ER becomes trapped...

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Detalles Bibliográficos
Autores principales: Wu, Minnie M., Covington, Elizabeth D., Lewis, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230625/
https://www.ncbi.nlm.nih.gov/pubmed/25057023
http://dx.doi.org/10.1091/mbc.E14-06-1107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230625/
https://www.ncbi.nlm.nih.gov/pubmed/25057023
http://dx.doi.org/10.1091/mbc.E14-06-1107

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