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Measuring fast gene dynamics in single cells with time-lapse luminescence microscopy

Time-lapse fluorescence microscopy is an important tool for measuring in vivo gene dynamics in single cells. However, fluorescent proteins are limited by slow chromophore maturation times and the cellular autofluorescence or phototoxicity that arises from light excitation. An alternative is lucifera...

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Detalles Bibliográficos
Autores principales: Mazo-Vargas, Anyimilehidi, Park, Heungwon, Aydin, Mert, Buchler, Nicolas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230627/
https://www.ncbi.nlm.nih.gov/pubmed/25232010
http://dx.doi.org/10.1091/mbc.E14-07-1187